The dancer is a young woman that has long blue hair and pink diamonds near her left eye shaped like scratch marks. She wears a blue sleeveless shirt with multiple holes in it, a blue skirt also with multiple holes in it, and pink shoes with blue ruffles. She also wears a yellow undershirt, pink socks, a pink belt and blue and yellow wristbands. She has a cyan outline. She looks similar to Ke$ha.
In the remake, the dancer is in a slightly lighter hue.
The background is full of colored lightning drawings and some graffiti. Colored lightning strikes from off-screen. The lightnings bring the dancer to the screen. The floor is the same as Fame and Only Girl (In The World). The lamps are more far away from each other in the remake and the lightnings in the corners are now in full opacity.
There are 3 Gold Moves in this routine:
Gold Move 1: Lift your knee and throw your right fist up.
Gold Move 2: Put your right hand on your mouth and your left hand on your hip.
Gold Move 3: Put your right arm over your left hand and on the side of your face. This is the final move of the routine.
Junk (which refers to genitalia) and Drunk are censored and replaced with the three dots symbol (...), however, despite each being said twice, only one set of dots appears for each.
This is the second song with any censorship in the Just Dance series, the first being Bebe. However, in Bebe the censorship was already there from the song itself, which makes TiK ToK the first song to have censorship added by Ubisoft for the game.
TiK ToK and C'mon are the only songs by Ke$ha to not debut as DLCs.
Currently, this is the only Kesha song to never have become a DLC, after C'mon became a recycled DLC in Just Dance 2015.
Gold Move 2 was not originally intended to be a Gold Move, as shown in the gameplay of E3 2010, but it was added in the final version.
Additionally, the pictograms were slightly different. This was later changed.
In Just Dance Wii, this dancer demonstrates how to play the game with the photo "Follow the dancer on the screen like they're your reflection on a mirror"; however, the song does not appear in that game, but it appears in Just Dance Wii 2.
Along with Hot Stuff and U Can't Touch This, this song was temporarily removed from Just Dance Now on March 26, 2015. However, it was later returned later that day.
When the Just Dance Now release of the song was announced via social networks, the Just Dance: Greatest Hits coach was accidentally used instead of the Just Dance Now remake. 
The coach's hair is shorter on the menu icons of Just Dance 2, Greatest Hits and Wii 2.
In Just Dance Now, the lightning sound from the beginning is removed. In Just Dance Unlimited, and later in Just Dance Now, it is re-added, along with some giggling at the end of the track. This giggling came from the original track.
In Just Dance NowandUnlimited, the sound effect from Just Dance 2’s audible 1, 2, 3, 4 count in is still present at the start of the routine- you can distinctly hear "tap-tap-tap-tap" before the first lyric scrolls up.
This count in is synchronised with the flashing triangle or spotlight at the end of the pictogram bar.
In the remake, sometimes the pictograms appear slightly out of sync with the song but the flashing triangle and spotlight as well as the highlighting lyrics are not.
In the Just Dance Now files, a Beta pictogram can be found. It looks very similar to a pictogram used in the Just Dance 2/Greatest Hits/Wii 2 versions of the routine.
The three pink stripes on her right eye are mirrored on the avatar.
A red shadow of the dancer along with a red warning sign is used as a placeholder bubble while selecting a DLC from the store in Just Dance 2.
This coach appears in the intro of every Just Dance 3 preview gameplay, along with the coach from Firework.
The coach's eye tattoo is a little bit glitchy, as it sometimes disappears.
The song is referenced in some scoring detection files for the Extreme Version of Animals.